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Q: Blood group compatibility for marriage?

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Matching blood group before marriage is important. This is to prevent Rh incompatibility. Rh incompatibility can lead to erythroblastosis fetalis (Hemolytic disease of the newborn-HDN). Fetal RBC gets destroyed & newborn may get severe anaemia, jaundice. This jaundice is more severe than Physiological jaundice ( which is the most common and will usually resolve on its own).   In very severe form, a fetus may die due to heart failure. This is mediated by the antigen-antibodies reaction. Transfer of maternal antibodies across the placenta occurs. This happens when Rh +ve man marries Rh-ve lady.    So Rh +ve man should try to avoid marrying Rh-ve lady.   Matching blood groups for marriage :: Boy : A = Girl : A & AB  Boy : B = Girl : B & AB  Boy : O = Girl : O, A, B & AB  Boy : AB = Girl : AB  Boy : Rh+ve = Girl : Rh+ve  Boy : Rh-ve = Girl : Rh+ve & Rh-ve.    Blood groups that do not match for marriage :: Boy : A = Girl : O & B  Boy : B = Girl : O & A  Boy : AB = Girl : O, A & B  Boy : Rh+ve = Girl : Rh-ve.

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